Module 8 -Treating Depression Lab Part 1 (discussion 1) – mod 8 group 1
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Learn by Doing
In this activity, you will investigate the first questionrelated to the study described below.
Some features of this activity may not work well on a cell phoneor tablet. We highly recommend that you complete this activity on a computer.
Here are the directions and grading rubric forthe Learn by Doing discussion board exercises.
A list of StatCrunch directions isprovided at the bottom of this page.
Clinical depression is a recurrent illnessrequiring treatment and often hospitalization. Nearly 50% of people who have anepisode of major depression will have a recurrence within 2-3 years. Being ableto prevent the recurrence of depression in people who are at risk for thedisease would go a long way to alleviate the pain and suffering of patients.
During the 1980’s the federal government, through the National Institutes ofHealth (NIH), sponsored a large clinical trial to evaluate two drugs fordepression. There were 3 treatment groups. Patients received either Imipramine(Imip), Lithium (Li), or a Placebo (Pl). Researchers randomly assigned patientsto one of the 3 treatment groups and followed them for 2-4 years to track anyrecurrences of depression.
(Prien et al., Archives of General Psychiatry, 1984).
·Hospt: Which hospital the patient was from: Labeled1, 2, 3, 5 or 6
·Treat: 0=Lithium; 1=Imipramine; 2=Placebo
·Outcome: 0=Success 1=Failure (recurrence ofdepression)
·Time: Number of weeks until a recurrence (ifoutcome=1) or until study ended (if outcome=0)
·AcuteT: How long the patient was depressed beforethe start of the current study, measured in days
·Age: Age in years
·Gender: 1=Female 2=Male
If you have not done so already, downloadthe depression datafile (as always, if a login boxopens, just close it and then download the file). Then upload the file inStatCrunch.
We will analyze the data to answer the 1stresearch question: Which of the drugs (if either) was more successfulin preventing the recurrence of depression relative to the placebo?
In the previous lab-preparation activity, we determined that wewill analyze the data using a two-way table and conditional percentages.
1. Use StatCrunch to produce a two-waycontingency table. (directions)
Copy the table in your StatCrunch output window and paste it in your initialdiscussion post. (directions)
After you paste the content of the your StatCrunch output window into yourdiscussion post, keep the table titled Contingency table results: anddelete the Chi-Square results: table.
2. Analyze the data in your two-way table byfinding appropriate conditional percentages. Write eachconditional percentage as a ratio (e.g. 25 out of 40) and as a percentage (e.g.25/40 = 62.5%). Then write a sentence that explains the meaning of thepercentage in the context of the research question.
3. Draw a conclusion. Based on this study, whichdrug was the most effective in preventing the recurrence of depression? Supportyour conclusion using conditional percentages.